Risk Factors, The Main Mechanisms and Clinical Variants of Liver Damage. Principles of Diagnosis and Treatment of Medicinal Liver Lesions

The article presents current data on the problem of medicinal liver damage and a number of clinical observations of the author. The risk factors, main mechanisms and clinical variants of liver damage, as well as the principles of diagnosis and treatment of drug-induced liver damage are indicated.There isno strong correlation between the severity of changes in the biochemical parameters of liver damage and clinical symptoms, a high risk of coagulopathy, and the need for long-term multicomponent monitoring of liver function and hemostasis.